For your male patients with LUTS*
Reimagine Watchful Waiting

Enhance watchful waiting with standardized 320 mg lipidosterolic extract of Serenoa repens (LSESr), a saw palmetto extract dietary supplement1,2

For your male patients with LUTS*
Reimagine Watchful Waiting

Enhance watchful waiting with standardized 320 mg lipidosterolic extract of Serenoa repens (LSESr), a saw palmetto extract dietary supplement1,2

1st and only USP-Verified prostate health supplement1

Setting the standards

For medicines, dietary supplements, and foods for more than 200 years2

Independent verification

With strict science and FDA cGMP* to ensure3,4

  • Positive identity
  • Potency
  • Purity
  • Performance

Setting the standards

For medicines, dietary supplements, and foods for more than 200 years2

Independent verification

With strict science and FDA cGMP* to ensure3,4

  • Positive identity
  • Potency
  • Purity
  • Performance

Tested in a certified lab to meet USP standards

Manufactured in an FDA-registered facility

Tested for contaminants and adulterants

Meets Good Manufacturing Practice (GMP)

USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. See www.uspverified.org

1. USP. USP-Verified Dietary Supplements. https://www.quality- supplements.org/verified-products. Accessed July 17, 2021.
2. USP. About USP. https://www.usp.org/about. Accessed July 17, 2021.
3. USP. Good Manufacturing Practices (GMP) Audit Program. https://www.usp.org/verification-services/gmp-audit-program. Accessed July 17, 2021.
4. USP. Choosing a Quality Supplement. https://qualitymatters.usp.org/ choosing-quality-supplements. Accessed July 17, 2021.

Clinical evidence demonstrates effectiveness in men with LUTS*

LSESr 15-study meta analysis:

Clinically meaningful change in IPSS*

Overall -5.73 improvement in IPSS (clinically significant)1

1. Adapted from: Vela-Navarrete R, et al. BJU Int. 2018 Dec;122(6):1049-1065.


LSESr 15-study meta analysis:

Significant improvement in nighttime voids*

Overall improvement of -1.56 voids per night1

1. Adapted from: Vela-Navarrete R, et al. BJU Int. 2018 Dec;122(6):1049-1065.


LSESr delays worsening of LUTS
vs watchful waiting*

1. Adapted from: Djavan B, et al. World J Urol. 2005;23:253-256.

†2-year comparative study of LSESr vs watchful waiting assessing step change in IPSS from mild (IPSS 1-7) to moderate (IPSS 8-19) or severe (IPSS 20-35) at 6, 12, 18 and 24 months.

1. Adapted from: Djavan B, et al. World J Urol. 2005;23:253-256.


An established safety profile based on decades of clinical research and in-market use*

LSESr has established safety without sexual side effects*1-5

Male Sexual Function 4-item Questionnaire1-5
(Interest in sex, quality of erection, achievement of ejaculation, achievement of orgasm)

No impact on sexual function1-5

No known drug interactions6

No impact on PSA testing1,2,4,7,8-10

Adapted from:

  1. Carraro JC, et al. Prostate. 1996;29:231-240.
  2. Debruyne F, et al. Eur Urol. 2002;41:497-506.
  3. Latil A, et al. Prostate. 2015;75:1857-1867.
  4. Pytel YA, et al. Adv Ther. 2002;19:297-306.
  5. Zlotta AR, et al. Eur Urol. 2005;48:269-276
  6. Markowitz JS, et al. Clin Pharmacol Ther. 2003;74(6):536-542.
  7. Alcaraz A, et al. J Clin Med. 2020 Sep 9;9(9):2909.
  8. Hizli F, et al. Int Urol Nephro. 2007;39:879-886.
  9. Giannakopoulos X, et al. Adv Ther. 2002;19:285-296.
  10. Djavan B, et al. World J Urol. 2005;23(4):253-256.

Unique bioactive fatty-acid fingerprint for LSESr

Standardized to 85% - 95% total fatty acids

Lauric Acid Ratio: Fatty Acid (Fingerprint Identity)1

Average values from gas chromatography data over a 3-year period.

Average values from gas chromatography data over a 3-year period.

Range: 86.3 – 93.1% total fatty acids.

https://online.uspnf.com/uspnf/document/1_GUID-53E14A4F-6F17-4CF1-852C-C6547F5A79DB_5_en-US.

1. USP. Saw palmetto extract.In: USP-NF.Rockville, MD: USP; Nov 1, 2020

1. USP. Saw palmetto extract. In: USP-NF. Rockville, MD: USP; Nov 1, 2020.
https://online.uspnf.com/uspnf/document/1_GUID-53E14A4F-6F17-4CF1-852C-C6547F5A79DB_5_en-US.